Publications at University of Arkansas
2024
27. Gan Q, Fan C*. Orthogonal Translation for Site-Specific Installation of Post-translational Modifications. Chem Rev. 2024, 124(5):2805-2838.
26. Fatema N, Li X, Gan Q, Fan C*. Characterizing Lysine Acetylation of Glucokinase. Protein Sci. 2024, 33(1):e4845.
2023
25. Fatema N, Fan C*. Studying lysine acetylation of citric acid cycle enzymes by genetic code expansion. Mol. Microbiol. 2023, 119(5):551-559.
24. Andrews J, Gan Q, Fan C*. ‘Not-So-Popular’ Orthogonal Pairs in Genetic Code Expansion. Protein Sci. 2023, 32(2):e4559.
2022
23. Fatema N, Ceballos RM, Fan C*. Modifications of Cellulose-based Biomaterials for Biomedical Applications. Front. Bioeng. Biotechnol. 2022, 10:993711.
22. Jouha J, Li F, Fan C*, Yang D*, Xiong H*. Editorial: Engineering Nucleic Acids-based Functional Nanomaterials, Nanodrugs, and Biosensors. Front. Bioeng. Biotechnol. 2022, 10:915229.
21. Araujo J, Ottinger S, Venkat K, Gan Q, Fan C*. Studying acetylation of aconitase isozymes by genetic code expansion. Front. Chem. 2022, 10:862483.
2021
20. O’Donoghue P*, Heinemann IU*, and Fan C*. Editorial: Synthetic Nucleic Acids for Expanding Genetic Codes and Probing Living Cells. Front. Bioeng. Biotechnol. 2021, 9:720534.
19. Chen H, Wilson J, Ercanbrack C, Smith H, Gan Q, Fan C*. Genome-Wide Screening of Oxidizing Agent Resistance Genes in Escherichia coli. Antioxidants. 2021, 10(6):861.
18. Chen H, Wilson J, Ottinger S, Gan Q, Fan C*. Introducing noncanonical amino acids for studying and engineering bacterial microcompartments. Current Opinion in Microbiology. 2021; 61:67-72.
2020
17. Chen H, Gan Q, Fan C*. Methyl-coenzyme M reductase and its post-translational modifications. Front. Microbiol. 2020; 11:578356.
16. Phipps JD, Chen H, Donovan CL, Dominguez DT, Morgan SR, Weidman BE, Fan C, and Beyzavi MH. Catalytic Activity, Stability, and Loading Trends of Alcohol Dehydrogenase Enzyme Encapsulated in a Metal–Organic Framework. ACS Applied Materials & Interfaces 2020; 12(23): 26084–26094.
15. Chen H, Ercanbrack C, Wang T, Gan Q, Fan C*. A Synthetic Reporter for Probing Mistranslation in Living Cells. Front. Bioeng. Biotechnol. 2020; 8:623.
2019
14. Venkat S, Chen H, McGuire P, Stahman A, Gan Q, Fan C*. Characterizing Lysine Acetylation of Escherichia coli Type II Citrate Synthase. FEBS J. 2019; 286(14): 2799-2808.
13. Venkat S, Chen H, Gan Q, Fan C*. The Application of Cell-free Protein Synthesis in Genetic Code Expansion for Post-translational Modifications. Front Pharmacol. 2019; 10:248.
12. Chen H, Venkat S, Hudson D, Wang T, Gan Q, Fan C*. Site-specifically Studying Lysine Acetylation of Aminoacyl-tRNA Synthetases. ACS Chem. Biol. 2019; 14(2):288-295.
2018
11. Chen H, Venkat S, Wilson J, McGuire P, Chang A, Gan Q, Fan C*. Genome-wide Quantification of the Effect of Gene Overexpression on Escherichia coli Growth. Genes. 2018; 9(8):414.
10. Chen H, Venkat S, McGuire P, Gan Q, Fan C*. Recent Development of Genetic Code Expansion for Posttranslational Modification Studies. Molecules. 2018; 23(7):1662.
9. Venkat S, Chen H, Stahman A, Hudson D, McGuire P, Gan Q, Fan C*. Characterizing lysine acetylation of isocitrate dehydrogenase in Escherichia coli. J. Mol. Biol. 2018; 430(13):1901-1911.
8. Venkat S, Sturges J, Stahman A, Gregory C, Gan Q, Fan C*. Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously. ACS Synth. Biol. 2018; 7(2):689-695.
2017
7. Venkat S, Gregory C, Meng K, Gan Q, Fan C*. A facile protocol to generate site-specifically acetylated proteins in Escherichia coli. J. Vis. Exp. 2017; 130:e57061.
6. Bryson D, Fan C, Guo L-T, Miller C, Söll D, Liu D. Continuous directed evolution of aminoacyl-tRNA synthetases to alter amino acid specificity and enhance activity. Nat. Chem. Biol. 2017; 13(12):1253-1260.
5. Venkat S, Nannapaneni DT, Gregory C, Gan Q, McIntosh M*, Fan C*. Genetically Encoding Thioacetyl-lysine as a Nondeacetylatable Analog of Lysine Acetylation in Escherichia coli. FEBS Open Bio. 2017; 7(11):1805-1814.
4. Venkat S, Gregory C, Gan Q, Fan C*. Biochemical Characterization of Lysine Acetylation of Tyrosyl-tRNA Synthetase in Escherichia coli. ChemBioChem. 2017; 18(19):1928-1934.
3. Venkat S, Gregory C; Sturges J, Gan Q, Fan C*, Studying the Lysine Acetylation of Malate Dehydrogenase. J. Mol. Biol. 2017; 429(9):1396-1405.
2. Gan Q and Fan C*, Increasing the Fidelity of Noncanonical Amino Acid Incorporation in Cell-Free Protein Synthesis. Biochimica et Biophysica Acta. 2017; 1861(11 Pt B):3047-3052.
2016
1. Gan Q, Lehman BP, Bobik TA and Fan C*, Expanding the genetic code of Salmonella with non-canonical amino acids. Scientific Reports. 2016; 6:39220.
Selected Publications During Postdoc and PhD Training
11. Fan C*, Ip K, Söll D. Expanding the genetic code of Escherichia coli with phosphotyrosine. FEBS Lett. 2016; 590(17):3040-3047.
10. Xiong H, Reynolds N, Fan C et al. Dual genetic encoding of acetyl-lysine and non-deacetylatable thioacetyl-lysine mediated by flexizyme. Angew. Chem. Int. Ed. Engl. 2016; 55(12):4083-4086.
9. Fan C*, Xiong H, Reynolds N, and Söll D. Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids. Nucleic Acids Res. 2015; 43(22):e156.
8. Amiram M, Haimovich A, Fan C et al. Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nat. Biotechnol. 2015; 33(12):1272-1279.
7. Fan C, Ho J, Chirathivat N, Söll D, and Wang Y-S. Exploring the substrate range of wild-type aminoacyl-tRNA synthetases. ChemBioChem. 2014; 15(12):1805-1809.
6. Fan C, Cheng S, Sinha S and Bobik TA. Interactions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartments. Proc. Natl. Acad. Sci. USA. 2012; 09(37):14995-15000.
5. Fan C and Bobik TA. The N-terminal region of the medium subunit (PduD) packages adenosylcobalamin-dependent diol dehydratase (PduCDE) into the Pdu micro-compartment. J. Bacteriol. 2011; 193(20):5623-5628.
4. Fan C, Cheng S, Liu Y et al. Short N-terminal sequences package proteins into bacterial microcompartments. Proc. Natl. Acad. Sci. USA. 2010; 107 (16):7509-7514.
3. Fan C, Fromm HJ, and Bobik TA. Kinetic and functional analysis of L-threonine kinase, the PduX enzyme of Salmonella enterica. J. Biol. Chem. 2009; 284(30): 20240-20248.
2. Fan C and Bobik TA. The PduX enzyme of Salmonella enterica is an L threonine kinase used for coenzyme B12 synthesis. J. Biol. Chem. 2008; 283(17):11322-11329.
1. Fan C and Bobik TA. Functional characterization and mutation analysis of human ATP:Cob(I)alamin adenosyltransferase. Biochemistry. 2008; 47(9):2806-2813.
Complete List of Published Work in PubMed:
Complete list of Publications