Publications at University of Arkansas
31. Li X, Gan Q, Fan C*. Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655. BMC Microbiol. 2026,
30. Tabatabaei RT, Alraawi Z, Fan C, Adams P, Kumar TKS. Incorporation of unnatural amino acid into human acidic fibroblast growth factor 1 (FGF1) protein with increased thermal, chemical stability and enhanced bioactivity. Arch Biochem Biophys. 2026, 776:110706.
29. Andrews J, Sakon J, Fan C*. Crystal structures of Escherichia coli Glucokinase and insights into phosphate binding. Acta Cryst. 2025, F81: 332-337.
28. Li X, Fatema N, Gan Q, Fan C*. Studying Lysine Acetylation of Phosphofructokinase Isozymes. FEBS J. 2025, 292(10):2545-2558.
27. Gan Q, Fan C*. Orthogonal Translation for Site-Specific Installation of Post-translational Modifications. Chem Rev. 2024, 124(5):2805-2838.
26. Fatema N, Li X, Gan Q, Fan C*. Characterizing Lysine Acetylation of Glucokinase. Protein Sci. 2024, 33(1):e4845.
25. Fatema N, Fan C*. Studying lysine acetylation of citric acid cycle enzymes by genetic code expansion. Mol. Microbiol. 2023, 119(5):551-559.
24. Andrews J, Gan Q, Fan C*. ‘Not-So-Popular’ Orthogonal Pairs in Genetic Code Expansion. Protein Sci. 2023, 32(2):e4559.
23. Fatema N, Ceballos RM, Fan C*. Modifications of Cellulose-based Biomaterials for Biomedical Applications. Front. Bioeng. Biotechnol. 2022, 10:993711.
22. Jouha J, Li F, Fan C*, Yang D*, Xiong H*. Editorial: Engineering Nucleic Acids-based Functional Nanomaterials, Nanodrugs, and Biosensors. Front. Bioeng. Biotechnol. 2022, 10:915229.
21. Araujo J, Ottinger S, Venkat S, Gan Q, Fan C*. Studying acetylation of aconitase isozymes by genetic code expansion. Front. Chem. 2022, 10:862483.
20. O’Donoghue P*, Heinemann IU*, and Fan C*. Editorial: Synthetic Nucleic Acids for Expanding Genetic Codes and Probing Living Cells. Front. Bioeng. Biotechnol. 2021, 9:720534.
19. Chen H, Wilson J, Ercanbrack C, Smith H, Gan Q, Fan C*. Genome-Wide Screening of Oxidizing Agent Resistance Genes in Escherichia coli. Antioxidants. 2021, 10(6):861.
18. Chen H, Wilson J, Ottinger S, Gan Q, Fan C*. Introducing noncanonical amino acids for studying and engineering bacterial microcompartments. Current Opinion in Microbiology. 2021; 61:67-72.
17. Chen H, Gan Q, Fan C*. Methyl-coenzyme M reductase and its post-translational modifications. Front. Microbiol. 2020; 11:578356.
16. Phipps JD, Chen H, Donovan CL, Dominguez DT, Morgan SR, Weidman BE, Fan C, and Beyzavi MH. Catalytic Activity, Stability, and Loading Trends of Alcohol Dehydrogenase Enzyme Encapsulated in a Metal–Organic Framework. ACS Applied Materials & Interfaces 2020; 12(23): 26084–26094.
15. Chen H, Ercanbrack C, Wang T, Gan Q, Fan C*. A Synthetic Reporter for Probing Mistranslation in Living Cells. Front. Bioeng. Biotechnol. 2020; 8:623.
14. Venkat S, Chen H, McGuire P, Stahman A, Gan Q, Fan C*. Characterizing Lysine Acetylation of Escherichia coli Type II Citrate Synthase. FEBS J. 2019; 286(14): 2799-2808.
13. Venkat S, Chen H, Gan Q, Fan C*. The Application of Cell-free Protein Synthesis in Genetic Code Expansion for Post-translational Modifications. Front Pharmacol. 2019; 10:248.
12. Chen H, Venkat S, Hudson D, Wang T, Gan Q, Fan C*. Site-specifically Studying Lysine Acetylation of Aminoacyl-tRNA Synthetases. ACS Chem. Biol. 2019; 14(2):288-295.
11. Chen H, Venkat S, Wilson J, McGuire P, Chang A, Gan Q, Fan C*. Genome-wide Quantification of the Effect of Gene Overexpression on Escherichia coli Growth. Genes. 2018; 9(8):414.
10. Chen H, Venkat S, McGuire P, Gan Q, Fan C*. Recent Development of Genetic Code Expansion for Posttranslational Modification Studies. Molecules. 2018; 23(7):1662.
9. Venkat S, Chen H, Stahman A, Hudson D, McGuire P, Gan Q, Fan C*. Characterizing lysine acetylation of isocitrate dehydrogenase in Escherichia coli. J. Mol. Biol. 2018; 430(13):1901-1911.
8. Venkat S, Sturges J, Stahman A, Gregory C, Gan Q, Fan C*. Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously. ACS Synth. Biol. 2018; 7(2):689-695.
7. Venkat S, Gregory C, Meng K, Gan Q, Fan C*. A facile protocol to generate site-specifically acetylated proteins in Escherichia coli. J. Vis. Exp. 2017; 130:e57061.
6. Bryson D, Fan C, Guo L-T, Miller C, Söll D, Liu D. Continuous directed evolution of aminoacyl-tRNA synthetases to alter amino acid specificity and enhance activity. Nat. Chem. Biol. 2017; 13(12):1253-1260.
5. Venkat S, Nannapaneni DT, Gregory C, Gan Q, McIntosh M*, Fan C*. Genetically Encoding Thioacetyl-lysine as a Nondeacetylatable Analog of Lysine Acetylation in Escherichia coli. FEBS Open Bio. 2017; 7(11):1805-1814.
4. Venkat S, Gregory C, Gan Q, Fan C*. Biochemical Characterization of Lysine Acetylation of Tyrosyl-tRNA Synthetase in Escherichia coli. ChemBioChem. 2017; 18(19):1928-1934.
3. Venkat S, Gregory C; Sturges J, Gan Q, Fan C*, Studying the Lysine Acetylation of Malate Dehydrogenase. J. Mol. Biol. 2017; 429(9):1396-1405.
2. Gan Q and Fan C*, Increasing the Fidelity of Noncanonical Amino Acid Incorporation in Cell-Free Protein Synthesis. Biochimica et Biophysica Acta. 2017; 1861(11 Pt B):3047-3052.
1. Gan Q, Lehman BP, Bobik TA and Fan C*, Expanding the genetic code of Salmonella with non-canonical amino acids. Scientific Reports. 2016; 6:39220.
Selected Publications During Postdoc and PhD Training
11. Fan C*, Ip K, Söll D. Expanding the genetic code of Escherichia coli with phosphotyrosine. FEBS Lett. 2016; 590(17):3040-3047.
10. Xiong H, Reynolds N, Fan C et al. Dual genetic encoding of acetyl-lysine and non-deacetylatable thioacetyl-lysine mediated by flexizyme. Angew. Chem. Int. Ed. Engl. 2016; 55(12):4083-4086.
9. Fan C*, Xiong H, Reynolds N, and Söll D. Rationally evolving tRNAPyl for efficient incorporation of noncanonical amino acids. Nucleic Acids Res. 2015; 43(22):e156.
8. Amiram M, Haimovich A, Fan C et al. Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nat. Biotechnol. 2015; 33(12):1272-1279.
7. Fan C, Ho J, Chirathivat N, Söll D, and Wang Y-S. Exploring the substrate range of wild-type aminoacyl-tRNA synthetases. ChemBioChem. 2014; 15(12):1805-1809.
6. Fan C, Cheng S, Sinha S and Bobik TA. Interactions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartments. Proc. Natl. Acad. Sci. USA. 2012; 09(37):14995-15000.
5. Fan C and Bobik TA. The N-terminal region of the medium subunit (PduD) packages adenosylcobalamin-dependent diol dehydratase (PduCDE) into the Pdu micro-compartment. J. Bacteriol. 2011; 193(20):5623-5628.
4. Fan C, Cheng S, Liu Y et al. Short N-terminal sequences package proteins into bacterial microcompartments. Proc. Natl. Acad. Sci. USA. 2010; 107 (16):7509-7514.
3. Fan C, Fromm HJ, and Bobik TA. Kinetic and functional analysis of L-threonine kinase, the PduX enzyme of Salmonella enterica. J. Biol. Chem. 2009; 284(30): 20240-20248.
2. Fan C and Bobik TA. The PduX enzyme of Salmonella enterica is an L threonine kinase used for coenzyme B12 synthesis. J. Biol. Chem. 2008; 283(17):11322-11329.
1. Fan C and Bobik TA. Functional characterization and mutation analysis of human ATP:Cob(I)alamin adenosyltransferase. Biochemistry. 2008; 47(9):2806-2813.
Complete List of Published Work in PubMed:
Complete list of Publications